Bookmark Kaumudi Online  Bookmark this site  Editor@Kaumudi  |  Marketing  Print Advt rates  |  Calendar 2018        Go!    
 
 
July 23, Monday 2018 2:08 AM       

       HEADLINES: CPM set to expand LDF                                              Man stabs son to death                                              Security beefed up at nun’s convent, interrogation of bishop delayed                                              Withdrawing novel an embarrassment for Kerala, says Chennithala                                              VS discharged from hospital                                              Three militants killed in Kashmir encounter                                              Two arrested for killing sister-in-law                                              Herald case: Vora moves court seeking to restrain Swamy                                              Actor Siddharth Shukla's BMW rams into three cars                                              BJP submits privilege notice against Rahul Gandhi for 'misleading' Parliament                                              Lawyers meet jailed Sharifs                                              One dead in US supermarket shooting, suspect arrested                                              Israel's LGBT community protests for fathers' surrogacy rights                                              Key to Root's ODI success was picking Kuldeep from his hand: Tendulkar                                              Bumrah's surgery in England ‘not a great success’, fitness before Tests in doubt                                              Kaumudi Facebook
       SCI&TECH Next Article: Google announces best apps of 2017  
       Researchers discover genes to prolong human life
 
         Posted on :18:07:36 Dec 8, 2017
   
A A
       Last edited on:18:07:36 Dec 8, 2017
         Tags: Researchers discover genes to prolong human l
 

WASHINGTON DC: A team of researchers has recently discovered new genes linked to parents' lifespan, which can one day be targeted to help prolong human life.

According to the University Of Exeter Devon, South West England, United Kingdom researchers, genetics and how long our parental relatives lived also plays a role.

Now, the number of genes we know influence lifespan has expanded, potentially paving the way to new therapeutic targets to prolong life.

The team studied 389,166 volunteers who took part in the UK Biobank, with confirmation in the US Health and Retirement Study and the Wisconsin Longitudinal Study.

They undertook a genome-wide search for variants influencing how long participants' parents lived.

The DNA samples from the volunteers carry the genetics of their biological parents, so provide a practical way of studying exceptionally long lifespans.

Eight genetic variants had already been linked for lifespan, mainly involved in heart disease and dementia.

The latest study has expanded this to 25 genes in all, with some specific to mothers' or fathers' lifespan separately.

Study author Dr Luke Pilling said: "We have identified new pathways that contribute to survival, as well as confirming others. These targets, including inflammatory and cardiovascular pathways, offer potentially modifiable targets to reduce risk of an earlier death and improve health."

Genes involved in senescence, the 'frozen' state that cells enter into after being damaged, played an important role in longevity.

Genes related to inflammation and auto-immunity related genes were also prominent, opening up the possibility that precision anti-inflammatory treatments may one day be helpful in extending life.

The results confirm that many genetic variants combine to influence human lifespan: no single gene variant was found to be responsible.

The study found evidence to suggest that the genetic variants for average lifespan also influence exceptionally long life expectancy.

A genetic risk score combining the top ten variants was statistically associated with parents being centenarians.

Lead researcher David Melzer said the study help open the way to novel treatment, but the strong role for genes affecting heart disease risk again underlines the importance of controlling blood pressure and cholesterol levels throughout the lifespan.

Of course, adopting healthy lifestyles is important, and can probably overcome the negative effects of most of the genes found so far, the researchers concluded.

The research appears in the journal Aging NY.

A A
       SCI&TECH
Next Article: Google announces best apps of 2017
 
 
SCI&TECH HEADLINES
NASA prepares to fly probe into Sun's scorching atmosphere  
Yoga helps against non-communicable diseases: WHO  
Spironolactone can help prevent acne: Study  
Older Amazonian forests help regulate global climate  
Goal conflict linked to depressive symptoms  
A new world: Top 10 new species for 2018  
Beat the risk of frailty with healthy heart  
Twitter to hide trolls that hurl abuse: Twitter CEO  
Fortnite is finally coming to Android  
This test could detect signs of pancreatic cancer  
Aliens exist but may be in parallel Universe: Study  
This is your heart on nitric oxide  
Is your kid's heart clock ticking right?  
Do at-risk adolescents show depressive symptoms on social media?  
NASA launches Insight spacecraft to Mars for deepest dig yet  
Daily intake of this drug can cause certain cancers in men  
A new weapon against epilepsy  
Hail stone weighing three kg sign of climate change: Expert  
PMSing? Could be because of alcohol!  
Social media firms given a week to better protect kids  
The stronger you are, the healthier your brain is  
NASA may soon identify 2,400 alien planets  
What triggers depression among adults?  
Turn your hobbies into part-time job opportunities with these apps  
Apple launches special RED Edition for iPhone 8, 8 Plus  
 
Do you support women's entry in Sabarimala?
Yes
 
No
 
Don't Know
 
 
 
Home Kerala India World Business Sports Sci&Tech Education Automobile CityNews Movies Environment Letters 
© Copyright keralakaumudi Online 2011  |  Reproduction in whole or in part without written permission is prohibited.
Head Office Address: Kaumudi Buildings, Pettah P.O, Trivandrum - 695024, India.
Online queries talk to Deepu Sasidharan, + 91 98472 38959 or Email deepu[at]kaumudi.com
Customer Service -Advertisement Disclaimer Statement   |  Copyright Policy