Bookmark Kaumudi Online  Bookmark this site  Editor@Kaumudi  |  Marketing  Print Advt rates  |  Calendar 2012        Go!    
 
 
February 26, Sunday 2017 8:13 PM       

       HEADLINES: Attack on actress: Prime accused brought to Coimbatore for evidence collection                                              Kunhalikutty selected League national general secretary                                              Afghanistan: ISIS recruit from Kerala killed in drone strike                                              Attack on actress: Probe should be handed over to trusted agency                                              Two killed in bus-car collision                                              South Indian comedian Thavakkala dies                                              India needs more scientists to harness technology: Modi                                              Gujarat ATS arrests suspected ISIS operatives                                              PIA had seven passengers standing during Karachi-Madina flight                                              Kohli, Ashwin unmoved in latest ICC Test Rankings                                              Kaumudi Facebook
       SCI&TECH Next Article: New potent vaccine may spell end for HIV  
       Predatory bacteria may wipe out 'superbugs': study
 
         Posted on :20:02:53 Nov 28, 2016
   
A A
       Last edited on:20:02:53 Nov 28, 2016
         Tags: Predatory bacteria, superbugs
 
LONDON: Predatory bacteria - that eat others of their kind - could be a new weapon in the fight against drug-resistant bacteria or 'superbugs', a new study suggests.
 
A naturally occurring predatory bacterium is able to work with the immune system to clear multi-drug resistant Shigella infections in zebrafish, researchers from Imperial College London and Nottingham University in the UK said.
 
It is the first time the predatory bacterium Bdellovibrio bacteriovorus has been successfully used as an injected anti-bacterial therapy and represents an important step in the fight against drug-resistant infections, or 'superbugs'.
 
Shigella infection is responsible for over 160 million illnesses and over one million deaths every year - and is a common cause of travellers' diarrhoea.
 
Cases of drug-resistant Shigella are also on the rise as, although the diarrhoea usually clears up without treatment, antibiotics are often used even in mild cases to stop the diarrhoea faster.
 
To investigate Bdellovibrio's ability to control drug resistant Gram-negative infections, researchers injected zebrafish larvae with a lethal dose of Shigella flexneri strain M90T, resistant to both streptomycin and carbenicillin antibiotics.
 
Bdellovibrio was injected into the larvae's infection site and a decrease in the number of Shigella was seen.
 
In the absence of Bdellovibrio, zebrafish were unable to control the replication of Shigella and levels of the bacteria rose.
 
"This study really shows what a unique and interesting bacterium Bdellovibrio is as it presents this amazing natural synergy with the immune system and persists just long enough to kill prey bacteria before being naturally cleared," said Serge Mostowy, from Imperial College London.
 
"It's an important milestone in research into the use of a living antibiotic that could be used in animals and humans," Mostowy said.
 
Bdellovibrio can invade and kill a range of Gram-negative bacteria, such as E coli and Salmonella, in the natural environment.
 
Previous research has shown that it can reduce pathogen numbers in the stomach of chickens when taken as an oral therapy, but there is growing need to develop therapies to target infections in wounds and organs.
 
Successful use of Bdellovibrio highlights its potential uses in tackling a range of drug-resistant Gram-negative bacterial infections that can develop in hospital patients.
 
"This has been a truly ground-breaking collaboration that shows therapeutic Bdellovibrio in action inside the translucent living zebrafish," Professor Liz Sockett, from The University of Nottingham said.
 
"The predatory action of the Bdellovibrio breaks the Shigella-pathogen cells and this stimulates the white blood cells; redoubling their 'efforts' against the pathogen and leading to increased survival of the zebrafish 'patients'," said Sockett.
 
The study was published in the journal Current Biology.
A A
       SCI&TECH
Next Article: New potent vaccine may spell end for HIV
 
 
SCI&TECH HEADLINES
NASA may put astronauts on deep space test flight  
Juno to remain in current orbit around Jupiter: NASA  
US man receives new face from donor  
Over 100 new potential planets spotted  
ISRO to launch record 104 satellites on Feb 15  
Now, video-makers can live stream on YouTube  
Music, drugs stimulate same part of brain: study  
Facebook adds tool for helping in times of crisis  
Moon may have formed from collision of tiny 'moonlets'  
China to set up world's highest altitude telescopes in Tibet  
NASA to launch two robotic probes to study early solar system  
After Mars, ISRO eyes Venus and Jupiter  
New, rare galaxy spotted over 359 mln light-years away  
Coconut sized tumor removed from Iraqi woman's head  
Bacteria-powered battery built on single sheet of paper  
'Human-made objects on Earth amount to 30 trillion tonnes'  
Element 117 officially named 'Tennessine'  
Predatory bacteria may wipe out 'superbugs': study  
New potent vaccine may spell end for HIV  
Water exists deeper in Earth than thought: study  
Docs reconstruct tongue with flesh from thigh  
Why wounds take longer to heal with age decoded  
WhatsApp launches video calling to take on Google Duo, Skype  
Molecules on phone can unveil your lifestyle: study  
Chandrayaan-2 mission: ISRO conducts tests for Moon landing  
 
Do you suspect controversy behind attack on the actress?
Yes
 
No
 
Don't kow
 
 
 
Home Kerala India World Business Sports Sci&Tech Education Automobile CityNews Movies Environment Letters 
© Copyright keralakaumudi Online 2011  |  Reproduction in whole or in part without written permission is prohibited.
Head Office Address: Kaumudi Buildings, Pettah P.O, Trivandrum - 695024, India.
Online queries talk to Deepu Sasidharan, + 91 98472 38959 or Email deepu[at]kaumudi.com
Customer Service -Advertisement Disclaimer Statement   |  Copyright Policy